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Current clinical trials at Bay Area Hospital


Kidney

S0931: Site PI: Bret Cook, MD. “EVEREST”: EVErolimus for Renal Cancer Ensuing Surgical Therapy, A Phase III Study. This study is trying to see if using everolimus after surgical removal of kidney cancer will increase the time without cancer returning. Further information available at http://clinicaltrials.gov/ct2/show/NCT01120249
 
Lung Cancer
 
CALGB 30607: Site PI: Bret Cook, MD. Sunitinib as Maintenance Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Treated With Combination Chemotherapy. This trial is comparing how well sunitinib works when given as maintenance therapy compared to a placebo in patients with stage III or stage IV non-small cell lung cancer previously treated with combination chemotherapy. http://clinicaltrials.gov/ct2/show/NCT00693992
  
E1505: Site PI: Bret Cook, MD. Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-Small Lung Cancer That Was Removed By Surgery. This trial is studying chemotherapy and bevacizumab to see how well they work compared to chemotherapy alone in treating patients with stage IB, stage II, or stage IIIA non-small cell lung cancer that was removed by surgery. Further information available http://clinicaltrials.gov/ct2/show/NCT00324805
 
Melanoma
  
E1609: Site PI: Bret Cook, MD. A Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy versus High-Dose Interferon a-2b for Resected High-Risk Melanoma. This clinical trial is studying ipilimumab or high-dose interferon alfa-2b in treating patients with high-risk stage III or stage IV melanoma that has been removed by surgery. Further information available http://clinicaltrials.gov/ct2/show/NCT01274338
 
Miscellaneous
  
S0702: Site PI: Bret Cook, MD. A Prospective Observational Multicenter Cohort Study to Assess the Incidence of Osteonecrosis of the Jaw (ONJ) in Cancer Patients With Bone Metastases Starting Zoledronic Acid. This trial is gathering information about how often osteonecrosis of the jaw occurs in patients receiving zoledronic acid (Zometa) for bone metastases and may help doctors learn more about the disease and provide the best follow-up care. Further information available http://clinicaltrials.gov/ct2/show/NCT00874211
 
Myelodysplastic Syndrome
 
E2905: Site PI: Bret Cook, MD. Lenalidomide With or Without Epoetin Alfa in Treating Patients with Myelodysplastic Syndrome and Anemia. This trial is studying lenalidomide (Revlamid) to see how well it works with or without epoetin alfa (Procrit) in treating patients with myelodysplastic syndrome and anemia. Further information available at http://clinicaltrials.gov/ct2/show/NCT00843882.
 
Prostate Cancer
 
CALGB 70807: Site PI: Leo Kusuda, MD. The Men's Eating and Living (MEAL) Study: A Randomized Trial of Diet to Alter Disease Progression in Prostate Cancer Patients on Active Surveillance. Further information available at http://clinicaltrials.gov/ct2/show/NCT01238172.
 
CALGB 90203: Site PI: Bret Cook, MD. Surgery With or Without Docetaxel and Leuprolide or Goserelin in Treating Patients with High-Risk Localized Prostate Cancer. This trial is studying docetaxel and leuprolide or goserelin to see how well they work when given before surgery compared with surgery alone in treating patients with high-risk localized prostate cancer. Further information available at http://clinicaltrials.gov/ct2/show/NCT00430183.
 

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